Soluble fibrin monomer complex is associated with cardio- and cerebrovascular events in patients with heart failure

Autor: Akiomi Yoshihisa, Yu Sato, Yusuke Kimishima, Yasuhiro Ichijo, Tetsuro Yokokawa, Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Kazuhiko Nakazato, Yasuchika Takeishi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 32, Iss , Pp 100697- (2021)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2020.100697
Popis: Background: A biomarker of fibrin formation, the soluble fibrin monomer complex (SFMC), is abnormally elevated in a variety of clinical situations of hypercoagulability. The aim of the present study was to examine the prognostic impact of SFMC, with regard to increased risk of major cardio- and cerebrovascular events (MACCE) and all-cause mortality, on patients with heart failure (HF). Methods and Results: We conducted a prospective observational study where we analyzed data of 723 hospitalized patients with decompensated HF who were discharged alive and whose SFMC had been measured in a stable condition prior to discharge. The patients were divided into tertiles based on SFMC levels: the first (SFMC
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