Celiac disease and Hp infection association in Iran Enfermedades celiacas e infección por Hp en Irán

Autor: M. Rostami-Nejad, V. Villanacci, R. Mashayakhi, M. Molaei, G. Bassotti, H. Zojaji, D. Mirstatari, K. Rostami, M. R. Zali
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2009
Předmět:
Zdroj: Revista Espanola de Enfermedades Digestivas, Vol 101, Iss 12, Pp 850-854 (2009)
Druh dokumentu: article
ISSN: 1130-0108
Popis: Background: we assessed the prevalence, the related symptoms, and the endoscopic and histologic gastric features of celiac disease (CD) in patients with Helicobacter pylori (Hp). Methods: 450 dyspeptic patients were studied. Biopsies of gastric antrum and duodenum, CD serology, and total IgA were obtained. Histological findings were scored with the Marsh-Rostami criteria. Results: 411 (91.3%) patients were Hp positive. Duodenal histology was normal in 385 (85.6%) patients, 124 (27.5%) had duodenitis and 28 (6.2%) showed duodenal abnormalities (Marsh I-IIIc). Twenty three/28 (82.1%) patients with malabsorption pattern were also Hp positive. Serological analysis: 12 of 31 (38.7%) positive patients had abnormal histology (Marsh I,-IIIc). Nine out 450 patients were IgA deficient; none of them was serologically positive for CD. Conclusion: although a high prevalence of Hp infection was found in this study, the relationship between Hp infection and CD was similar to that reported in other geographic areas.
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