Iron oxide nanoparticles in magnetic drug targeting and ferroptosis-based cancer therapy

Autor: Shubhra Quazi T. H.
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Medical Review, Vol 3, Iss 5, Pp 444-447 (2023)
Druh dokumentu: article
ISSN: 2749-9642
DOI: 10.1515/mr-2023-0029
Popis: Iron oxide (IO) nanoparticles (NPs) have gained significant attention in the field of biomedicine, particularly in drug targeting and cancer therapy. Their potential in magnetic drug targeting (MDT) and ferroptosis-based cancer therapy is highly promising. IO NPs serve as an effective drug delivery system (DDS), utilizing external magnetic fields (EMFs) to target cancer cells while minimizing damage to healthy organs. Additionally, IO NPs can generate reactive oxygen species (ROS) and induce ferroptosis, resulting in cytotoxic effects on cancer cells. This article explores how IO NPs can potentially revolutionize cancer research, focusing on their applications in MDT and ferroptosis-based therapy.
Databáze: Directory of Open Access Journals