| Autor: |
Amy C. Moreno, Christopher Wilke, He Wang, Shi-Ming Samuel Tung, Courtney Pollard, III, Adam S. Garden, William H. Morrison, David I. Rosenthal, Clifton D. Fuller, Gary B. Gunn, Jay P. Reddy, Shalin J. Shah, Steven J. Frank, Vinita Takiar, Jack Phan |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Physics and Imaging in Radiation Oncology, Vol 10, Iss , Pp 29-34 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6316 |
| DOI: |
10.1016/j.phro.2019.04.002 |
| Popis: |
Background and purpose: Minimizing radiation dose exposure to nearby organs is key to limiting clinical toxicities associated with radiotherapy. Several treatment modalities such as split- or whole-field intensity-modulated radiotherapy (SF-IMRT, WF-IMRT) and volumetric modulated arc therapy (VMAT) are being used to treat tonsillar cancer patients with unilateral neck radiotherapy. Herein, we provide a modern dosimetric comparison of all three techniques. Materials and methods: Forty patients with tonsillar cancer treated with definitive, ipsilateral neck SF-IMRT were evaluated. Each patient was re-planned with WF-IMRT and VMAT techniques, and doses to selected organs-at-risk (OARs) including the larynx, esophagus, and brainstem were compared. Results: No significant differences in target coverage existed between plans; however, the heterogeneity index improved using WF-IMRT and VMAT relative to SF-IMRT. Compared to SF-IMRT, WF-IMRT and VMAT plans had significantly lower mean doses to the supraglottic larynx (31 Gy, 18.5 Gy, 17 Gy; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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