Special Considerations on the Use of Vaccines for Immunoprophylaxis of Bacterial Infections
| Autor: | N. A. Gavrilova, Е. А. Ustyugova, N. F. Nikityuk, Yu. I. Obukhov, V. P. Bondarev |
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| Jazyk: | ruština |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Биопрепараты: Профилактика, диагностика, лечение, Vol 19, Iss 3, Pp 145-153 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2221-996X 2619-1156 |
| DOI: | 10.30895/2221-996X-2019-19-3-145-153 |
| Popis: | Mass vaccination is an essential element of immunoprophylaxis of infectious diseases, and the global community has agreed that it is crucial for preserving the lives and health of children and adults. The objective of this study was to analyse the current state of vaccination of infants under one year old against bacterial infections, given that the National Immunisation Schedule is overladen with various vaccines, and there are apparent inconsistencies between the types of marketed vaccines and recommendations on their use. The article summarises the types of antibacterial vaccines marketed in the Russian Federation, analyses some aspects of combination of different antigens and interchangeability of vaccines. The authors justify the need to amend recommendations on antibacterial vaccination and to develop common rules for the use and combination of vaccines, as well as for their interchangeability. Another important issue is adoption of requirements for the contents of patient information leaflets. The article summarises the main safety concerns regarding the use of polyvalent vaccines and simultaneous vaccination against several pathogens. It discusses safety issues of multiple immunisation and the strategy to reduce potential risks associated with an intensive vaccination schedule. The authors highlight the safety of current immunisations schedules and the need to update vaccination standards. They also demonstrate the need to harmonise national recommendations on the use of vaccines based on clinical data and the results of international clinical trials. |
| Databáze: | Directory of Open Access Journals |
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