Electrogenerated chemiluminescence peptide-based bioassay

Autor: Qi Honglan, Dang Qian, Dong Manman, Gao Hongfang, Li Min
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Reviews in Analytical Chemistry, Vol 33, Iss 4, Pp 255-263 (2014)
Druh dokumentu: article
ISSN: 0793-0135
2191-0189
DOI: 10.1515/revac-2014-0015
Popis: Electrogenerated chemiluminescence (ECL) involves the generation of species at electrode surfaces that then undergo electron-transfer reactions to form excited states that emit light. The ECL method is becoming an increasingly promising method in the life sciences, environmental analysis, and clinical analysis, owing to its good selectivity, high sensitivity, wide dynamic concentration response range, and potential and spatial controllability. Here, we give a mini-review on the advances of the ECL peptide-based bioassay using peptide as the molecular recognition element. First, a general history of ECL development is presented. Then, the general strategies of the ECL peptide-based bioassay are reviewed. Particular attention is paid to the related progress in the last 5 years. Finally, we conclude with the future challenges and prospects in the development of the ECL peptide-based bioassay.
Databáze: Directory of Open Access Journals