Vasopressin Receptor Antagonists (Vaptans) in Heart Failure

Autor:	Piotr Lipiec, Marco Metra
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	heart failure hyponatraemia tolvaptan vasopressin antagonists vaptans Medicine Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	International Cardiovascular Forum Journal, Vol 17, Pp 37-38 (2019)
Druh dokumentu:	article
ISSN:	2410-2636 2409-3424
DOI:	10.17987/icfj.v17i0.605
Popis:	Vasopressin receptor blockade is an interesting therapeutic target in patients with heart failure. To date, however, clinical trials of vasopressin antagonists have failed to demonstrate any significant benefits in term of long-term mortality or heart failurerelated morbidity. Limited short-term beneficial clinical effects reported in patients with acute heart failure, volume overload and resistant hyponatraemia translate into only a limited role of vaptans in recommended management of this patient population.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ec6cbea937a645d5803c9fc040b8af8e Zobrazit plný text záznamu View record in DOAJ