Considerations when Measuring Biocatalyst Performance

Autor:	Mafalda Dias Gomes, John M. Woodley
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	biocatalysis immobilized enzymes turnover number process performance metrics enzyme kinetics enzyme stability Organic chemistry QD241-441
Zdroj:	Molecules, Vol 24, Iss 19, p 3573 (2019)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules24193573
Popis:	As biocatalysis matures, it becomes increasingly important to establish methods with which to measure biocatalyst performance. Such measurements are important to assess immobilization strategies, different operating modes, and reactor configurations, aside from comparing protein engineered variants and benchmarking against economic targets. While conventional measurement techniques focus on a single performance metric (such as the total turnover number), here, it is argued that three metrics (achievable product concentration, productivity, and enzyme stability) are required for an accurate assessment of scalability.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6cbe04d0e96a42c6bc9068e2fba4af85 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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