Agr typing of Staphylococcus aureus species isolated from clinical samples in training hospitals of Isfahan and Shahrekord

Autor: Saeid Javdan, Tahmine Narimani, Milad Shahini Shams Abadi, Abolfazl Gholipour
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Druh dokumentu: article
ISSN: 1756-0500
DOI: 10.1186/s13104-019-4396-8
Popis: Abstract Objective As an opportunistic pathogen, Staphylococcus aureus is associated with serious nosocomial infections and growing antimicrobial resistance against beta-lactams among S. aureus strains has become a global challenge. The current study was designed to investigate the presence of agr genes among S. aureus strains recovered from clinical samples in university hospitals of Isfahan and Shahrekord. Results A total of 150 S. aureus isolates were screened by Disk diffusion method (DDM) and conventional PCR. The minimum (17.3%) and maximum (46%) antibiotic resistance rates were found in vancomycin and cefoxitin, respectively. The majority of our isolates were classified as agr type I followed by type II, type IV, and type III. The statistical analysis showed a significant correlation between agr type I and antibiotic resistance against cefoxitin and erythromycin (p = 0.04 and p = 0.03, respectively). Based on our findings, the agr typing could be considered an effective approach for molecular tracking of S. aureus infections.
Databáze: Directory of Open Access Journals
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