Flow diversion of cerebral aneurysms in Type I osteogenesis imperfecta: A case report of the first two treatments in humans

Autor: David A Zarrin, Jessica K Campos, Benjamen M Meyer, Alexander S Himstead, Fahad Laghari, Jonathan C Collard de Beaufort, Kiarash Golshani, Narlin B Beaty, Matthew T Bender, Geoffrey P Colby, Alexander L Coon
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: SAGE Open Medical Case Reports, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2050-313X
2050313X
DOI: 10.1177/2050313X241274243
Popis: Osteogenesis imperfecta (OI) predisposes individuals to easy bone fracture, vessel fragility, and platelet dysfunction. We report the first known case of neurointerventional treatment with flow diversion of intracranial aneurysms in a patient with OI. A 62 year-old female with known OI Type I, history of >40 lifetime bone fractures and hypertension, underwent workup for transient ischemic attacks revealing a 4-mm right A1 segment aneurysm in 2016. Perioperative dual antiplatelet therapy was aspirin 81 mg and clopidogrel 37.5 mg daily. Tri-axial access was utilized to deploy a 3.5 × 16-mm Pipeline Flex device without complication. Two-month follow-up revealed Raymond I (O’Kelly Marotta I) obliteration of the aneurysm. Five-year follow-up revealed a de novo left-sided 3-mm A1–A2 junction aneurysm. A 4 × 12-mm Surpass Evolve was placed without complication. Six-month follow-up revealed Raymond I (O’Kelly Marotta I) obliteration of the second aneurysm. The patient remained asymptomatic at all follow-up visits.
Databáze: Directory of Open Access Journals