Rhabdomyolysis in the Setting of Concomitant Use of Tafamidis, Atorvastatin, and Amiodarone

Autor: Jessica Laird, BA, Rodney H. Falk, MD, Melissa Coyle, PharmD, CSP, Sarah A.M. Cuddy, MB BCH, BAO
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: JACC: Case Reports, Vol 2, Iss 15, Pp 2372-2375 (2020)
Druh dokumentu: article
ISSN: 2666-0849
DOI: 10.1016/j.jaccas.2020.09.037
Popis: An 85-year-old women with transthyretin cardiac amyloidosis presented with generalized weakness, elevated liver function test levels, and creatinine kinase consistent with rhabdomyolysis 1 week after starting tafamidis. She was already taking atorvastatin and amiodarone, raising the possibility of a drug–drug interaction inhibiting the breakdown and excretion of atorvastatin, causing drug-induced rhabdomyolysis. (Level of Difficulty: Intermediate.)
Databáze: Directory of Open Access Journals