| Autor: |
Özlem Karakurt Arıtürk, Kemal Üreten, Münevver Sarı, Nuray Yazıhan, Evin Yılmaz, İmge Ergüder |
| Jazyk: |
English<br />Turkish |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Türk Kardiyoloji Derneği Arşivi, Vol 41, Iss 1, Pp 38-44 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
1016-5169 |
| DOI: |
10.5543/tkda.2013.10179 |
| Popis: |
Objectives: Familial Mediterranean fever (FMF) is an autosomal recessive disorder and the most frequent periodic syndrome characterized by recurrent attacks of polyserositis. Heart-type fatty acid-binding protein (h-FABP) is an intracellular molecule engaged in the transport of fatty acids through the myocardial cytoplasm and a rapid marker of myocardial injury. FMF is an autoinflammatory disease characterized by ongoing inflammatory activity. Inflammation also plays an important role in the development and progression of atherosclerosis in some rheumatic diseases. We aimed to investigate markers of atherosclerosis in patients with FMF by the measurement of serum h-FABP and malondialdehyde levels (MDA). Study design: Forty consecutive patients with FMF and twenty healthy volunteers were selected to participate in the study. The diagnosis of FMF was based on Tel-Hashomer criteria. Serum h-FABP and MDA levels were determined to examine the association. Results: The mean h-FABP level in FMF patients was significantly higher than the normal population (4.89+-0.83 vs. 3.06+-2.13 ng/ml, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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