Sarcomatoid variant of urothelial carcinoma of renal pelvis with direct invasion of the pancreas and descending colon

Autor: Yoshinori Nakano, Hiroyuki Kitano, Keisuke Hieda, Takashi Babasaki, Kenshiro Takemoto, Tetsutaro Hayashi, Aya Kido, Daiki Taniyama, Kazuhiro Sentani, Nobuyuki Hinata
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: IJU Case Reports, Vol 5, Iss 5, Pp 350-353 (2022)
Druh dokumentu: article
ISSN: 2577-171X
DOI: 10.1002/iju5.12479
Popis: Introduction Sarcomatoid variant of urothelial carcinoma infiltrates the perimeter and occurs occasionally. However, there are only few case reports. Case presentation A left renal tumor was incidentally detected in a 75‐year‐old woman and protruded outside the kidney, infiltrating the pancreatic tail and spleen. Tumor invasion was observed in the adjacent organs; therefore, the left kidney, pancreatic tail, spleen, and, descending colon were resected. Histopathological examination revealed a sarcomatoid variant of invasive urothelial carcinoma. She received two cycles of gemcitabine and carboplatin combination chemotherapy but succumbed to the disease after 5 months. Conclusion Sarcomatoid variant of urothelial carcinoma is rare, with aggressive malignancy. The diagnosis was difficult and required surgery. This is the first case of a sarcomatoid variant of urothelial carcinoma with direct invasion into the pancreas and descending colon.
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