Risk factors for urgent complications of colorectal cancer

Autor: S. N. Shchaeva
Jazyk: ruština
Rok vydání: 2022
Předmět:
Zdroj: Тазовая хирургия и онкология, Vol 12, Iss 2, Pp 28-35 (2022)
Druh dokumentu: article
ISSN: 2686-9594
DOI: 10.17650/2686-9594-2022-12-2-28-35
Popis: Objective: to identify the main factors associated with an increased risk of urgent complications of colorectal cancer.Materials and methods. This retrospective cohort study included 214 patients with colorectal cancer who had undergone emergency surgery in Smolensk hospitals between January 2016 and January 2020. Their median age was 66 years. We analyzed patients’ sociodemographic characteristics (sex, age, settings (urban or rural), education, employment, profession, and family status), disease history, clinical characteristics (type of urgent complication, comorbidities), morphological tumor characteristics (histological type, pTNM stage, pattern of tumor growth (exo- or endophytic, mixed), tumor length along the intestine (7 cm), presence of lymph node metastases and distant metastases). Multivariate logistic regression was used to analyze factors that were independently associated with an increased risk of decompensated intestinal obstruction and colon perforation.Results. The most significant risk factors for decompensated intestinal obstruction included T4 stage (odds ratio (OR) 3.19; 95 % confidence interval (CI) 1.66–7.12; p
Databáze: Directory of Open Access Journals