| Autor: |
Jenniffer Linares, Anna Sallent-Aragay, Jordi Badia-Ramentol, Alba Recort-Bascuas, Ana Méndez, Noemí Manero-Rupérez, Daniele Lo Re, Elisa I. Rivas, Marc Guiu, Melissa Zwick, Mar Iglesias, Carolina Martinez-Ciarpaglini, Noelia Tarazona, Monica Varese, Xavier Hernando-Momblona, Adrià Cañellas-Socias, Mayra Orrillo, Marta Garrido, Nadia Saoudi, Elena Elez, Pilar Navarro, Josep Tabernero, Roger R. Gomis, Eduard Batlle, Jorge Pisonero, Andres Cervantes, Clara Montagut, Alexandre Calon |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-023-36334-1 |
| Popis: |
Standard platinum-based chemotherapy is the basis of treatment of many cancers, however a proportion of patients do not derive benefit. Here the authors show that the platinum-based drug oxaliplatin accumulates in cancer-associated fibroblasts, activating pathways associated with cancer progression and resistance to therapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full text from SpringerLink