On the impact of improved dose calculation accuracy in clinical treatment planning for superficial high-dose-rate brachytherapy of extensive scalp lesions

Autor: Giulio Rossi, Vasiliki Peppa, Mark Gainey, Michael Kollefrath, Tanja Sprave, Panagiotis Papagiannis, Dimos Baltas
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Physics and Imaging in Radiation Oncology, Vol 32, Iss , Pp 100673- (2024)
Druh dokumentu: article
ISSN: 2405-6316
DOI: 10.1016/j.phro.2024.100673
Popis: TG-43-based dose calculations disregard tissue heterogeneities and finite scatter conditions, prompting the introduction of model-based dose calculation algorithms (MBDCAs) to improve accuracy in high-dose-rate (HDR) brachytherapy. This study evaluated the effectiveness of MBDCAs over TG-43 in HDR 192Ir brachytherapy of extended scalp lesions. Treatment planning dose calculations were compared with Monte Carlo (MC) data. TG-43 exhibited a dose overestimation ranging from 10% to 23% as the distance from the implant increased, while a better agreement from 2% to 6% was observed between the MBDCA and MC, supporting the adoption of MBDCAs for dose calculations in broad scalp lesions.
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