| Autor: |
Qing Huang, Yi Sun, Jing Lu, Qiu-Yu Huang, Yi-Le Zeng, Bang Liu, Xing-Yan Xu, Ying-Ying Cai, Shao-Wei Lin, Huang-Yuan Li, Si-Ying Wu |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Ecotoxicology and Environmental Safety, Vol 223, Iss , Pp 112609- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
0147-6513 |
| DOI: |
10.1016/j.ecoenv.2021.112609 |
| Popis: |
Objective: By exploring the exposure-response relationships between meteorological factors and rupture of intracranial aneurysm (IA) to reveal the influence of meteorological variation on IA rupture under the specific climate in Fujian, China. Method: 7515 cases of IA rupture from several municipal medical institutions in Fujian Province as well as local meteorological data during the same period were collected from 2013 to 2017. Poisson regression and Spearman correlation analysis were applied to explore the distribution characteristics of IA rupture and how it is associated with meteorological parameters. Poisson generalized additive model was established to further analyze the exposure-response relationships between meteorological factors and IA rupture, and its hysteresis effects. Result: The IA rupture exhibited a negative correlation with temperature (rs = −0.323, 95% CI: −0.539 ~ −0.068) and a positive correlation with atmospheric pressure (rs = 0.397, 95% CI: 0.152–0.597) or pressure difference (rs = 0.296, 95% CI: 0.038–0.517), 21.05 ℃ and 1000.14 hPa were the risk thresholds for the onset ascribed to variation in temperature and atmospheric pressure, respectively. Temperature and atmospheric pressure also exerted hysteresis effects on IA rupture. Cold will increase the rupture risk in the subsequent 1–3 days, and high pressure will raise the morbidity in the next 1–2 days. Besides, drastic variations in temperature and atmospheric pressure were also associated with the higher risk of IA rupture in the next 2 days and 1 day, respectively. Conclusion: Temperature and atmospheric pressure have a negative and positive correlation with IA rupture in Fujian, China, respectively. Variation in temperature and atmospheric pressure exert different degrees of hysteresis effects on IA rupture. |
| Databáze: |
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| Externí odkaz: |
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