The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery

Autor: Bin Zhang, Xu-Rui Liu, Xiao-Yu Liu, Bing Kang, Chao Yuan, Fei Liu, Zi-Wei Li, Zheng-Qiang Wei, Dong Peng
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Canadian Journal of Gastroenterology and Hepatology, Vol 2023 (2023)
Druh dokumentu: article
ISSN: 2291-2797
DOI: 10.1155/2023/2017171
Popis: Purpose. The current study was designed to investigate the impact of blood urea nitrogen (BUN), serum uric acid (UA), and cystatin (CysC) on the short-term outcomes and prognosis of colorectal cancer (CRC) patients undergoing radical surgery. Methods. CRC patients who underwent radical resection were included from Jan 2011 to Jan 2020 in a single clinical centre. The short-term outcomes, overall survival (OS), and disease-free survival (DFS) were compared in different groups. A Cox regression analysis was conducted to identify independent risk factors for OS and DFS. Results. A total of 2047 CRC patients who underwent radical resection were included in the current study. Patients in the abnormal BUN group had a longer hospital stay (p=0.002) and more overall complications (p=0.001) than that of the normal BUN group. The abnormal CysC group had longer hospital stay (p
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