Effect of Exercise on ADMA Level in Type 2 Diabetes Mellitus
| Autor: | Bengur Taşkıran, Betül Uğur Altun, Selma Arzu Vardar, Ahmet Muzaffer Demir, Çetin Hakan Karadağ, Armağan Altun |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Balkan Medical Journal, Vol 29, Iss 1, Pp 62-67 (2012) |
| Druh dokumentu: | article |
| ISSN: | 2146-3123 2146-3131 98086413 |
| Popis: | Objective: The increase in symmetric (SDMA) and asymmetric dimethyl arginine (ADMA) is associated with endothelial dysfunction. The aim of this study was to evaluate the effect of exercise on ADMA and SDMA levels and related ratios in type 2 DM.Material and Methods: Thirty-six women with type 2 DM and 44 healthy women were recruited to the study. Fourteen and 19 subjects, respectively, attended four-weeks of moderate intensity exercise. Plasma SDMA, ADMA, and L-arginine levels were measured by the HPLC method initially, after the first exercise session, and after one month. Results: All measurements were within the normal range in both groups and did not change significantly immediately after exercise and after the first month. In the healthy group, L-arginine/ADMA and L-arginine/SDMA ratios after one month were significantly higher than the initial values (p |
| Databáze: | Directory of Open Access Journals |
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