The Comparison of Irisin, Subfatin, and Adropin in Normal-Weight and Obese Polycystic Ovary Syndrome Patients

Autor: Alabbas Abdulkareem Majeed, Alaa Hussein J. Al-Qaisi, Waled Abdo Ahmed
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Iranian Journal of Medical Sciences, Vol 49, Iss 6, Pp 350-358 (2024)
Druh dokumentu: article
ISSN: 0253-0716
1735-3688
DOI: 10.30476/ijms.2023.99130.3117
Popis: Background: A combination of genetic and environmental factors contribute to the highly common, complex, and varied endocrine condition known as polycystic ovary syndrome (PCOS) in women. PCOS primarily affects women between the ages of 15 and 35 who are in the early to late stages of pregnancy. Thus, this study aimed to evaluate the serum levels of irisin, subfatin, and adropin in PCOS with and without obesity compared to the control group.Methods: The present cross-sectional study was conducted in 2022 at Al-Nahrain University/Department of Chemistry (Baghdad, Iraq). The serum levels of irisin, subfatin, and adropin were measured with the enzyme-linked immunosorbent assay (ELISA) method. Body mass index, lipid profile, insulin, fasting glucose, follicle-stimulating hormone, and luteinizing hormone levels were also evaluated. The data were analyzed using one-way analysis of variance (ANOVA) by GraphPad Prism software version 8.0.2. A P
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