Autor: |
Daniel Madriz Sørensen, Christian Büll, Thomas D. Madsen, Erandi Lira-Navarrete, Thomas Mandel Clausen, Alex E. Clark, Aaron F. Garretson, Richard Karlsson, Johan F. A. Pijnenborg, Xin Yin, Rebecca L. Miller, Sumit K. Chanda, Thomas J. Boltje, Katrine T. Schjoldager, Sergey Y. Vakhrushev, Adnan Halim, Jeffrey D. Esko, Aaron F. Carlin, Ramon Hurtado-Guerrero, Roberto Weigert, Henrik Clausen, Yoshiki Narimatsu |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-023-36598-7 |
Popis: |
Here, the authors discover small molecules that inhibit glycosylation processes that occur in the Golgi apparatus of cells. The molecules reversibly inhibit formation of elaborate glycan structures without affecting secretion of glycoproteins. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|