Geriatric anesthesia

Autor: Gyu-Jeong Noh
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Korean Journal of Clinical Oncology, Vol 9, Iss 2, Pp 76-79 (2013)
Druh dokumentu: article
ISSN: 1738-8082
2288-4084
DOI: 10.14216/kjco.13014
Popis: As a result of improvements in health care, nutrition, and general living standards, the average life expectancy and elderly population is increased worldwide. Aging is associated with a universal and progressive loss of functional reserve and degenerative changes in all organ systems. Although physiologic compensation for age-related changes may be adequate in most geriatric patients, the functional reserve of organ systems is reduced, and susceptibilities to stress- and disease-induced organ system decompensation can occur. Anticipating the interactions between underlying diseases, limited end-organ reserve, and perioperative stress should aid physicians in providing the best perioperative care possible. We review the age-related physiologic changes in organ systems and pharmacokinetic and pharmacodynamic changes of anesthetics in elderly surgical patients.
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