Comparative effectiveness and safety of prasugrel and ticagrelor in patients of acute coronary syndrome undergoing percutaneous transluminal coronary angioplasty: A propensity score-matched analysis

Autor: Avik Ray, Ahmad Najmi, Gaurav Khandelwal, Ratinder Jhaj, Balakrishnan Sadasivam
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Indian Heart Journal, Vol 76, Iss 2, Pp 133-135 (2024)
Druh dokumentu: article
ISSN: 0019-4832
DOI: 10.1016/j.ihj.2024.03.001
Popis: Evidence on comparative effectiveness and safety of prasugrel and ticagrelor post-percutaneous transluminal coronary angioplasty is scarce in Indian population. In a 1:1 propensity score-matched cohort with 71 individuals in each group, the incidence of a composite of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or coronary revascularization was not significantly different in prasugrel and ticagrelor group (7.04% vs 9.86%; absolute difference, 2.8%; HR, 0.65; 95% CI, 0.21–2.1; p = 0.49). There was no significant difference in bleeding (5.63% vs 9.86%; absolute difference, −4.20%; 95% CI, −13.0%–4.5%) and dyspnea (7.04% vs 12.7%; absolute difference, −5.60%; 95% CI, −15.4%–4.1%).
Databáze: Directory of Open Access Journals