Cardiac Troponin-I and COVID-19: a prognostic tool for in-hospital mortality
| Autor: | Hany William Z. Hanna, Randa Salam, Mohamed Mamdouh Youssef, Rokaya ABD El Aziz, Moustafa Saeed |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Alexandria Journal of Medicine, Vol 59, Iss 1, Pp 59-67 (2023) |
| Druh dokumentu: | article |
| ISSN: | 20905068 2090-5076 2090-5068 50354027 |
| DOI: | 10.1080/20905068.2023.2237757 |
| Popis: | ABSTRACTIntroduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused Coronavirus disease 2019 (COVID-19) emerging outbreak. In up to 15% of cases, the clinical course of the disease may get complicated to a severe form of interstitial pneumonia, acute respiratory distress syndrome (ARDS) and/or multi-organ failure (MOF) and death. So, our cross-sectional study was conducted to evaluate cardiac troponin I as a prognostic factor for poor in-hospital outcome in patients admitted with COVID-19 infection.Methods Study included 101 confirmed COVID-19 patients with age > 18 years old, of any gender, survivors (74 patients) and non-survivors (27 patients), with no history of any cardiac or pulmonary disease. They were subjected to medical history, clinical examination and laboratory investigations including cardiac troponin I, CBC, urea, creatinine, AST, ALT, CRP, D-Dimer, INR, Na, K and ABG. During their hospital stay, a comparison was done among all sociodemographic data, vital signs on admission, laboratory findings including troponin I level, clinical outcome (need for mechanical ventilation and length of mechanical ventilation if needed), CT chest, CORADS score and APACHI II score between both groups.Results The mean troponin levels showed statistically significant difference between COVID-19 survivors and non-survivors (P-value = 0.001). Significant lower number of survivors needed mechanical ventilation compared to the non survivors (p-value |
| Databáze: | Directory of Open Access Journals |
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