| Autor: |
Fatehi Elzein, Kiran Kalam, Nazik Mohammed, Ahmed Elzein, Fadhel Zaben Alotaibi, Mujtaba Khan, Abeer Albadani |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Medical Mycology Case Reports, Vol 23, Iss , Pp 4-7 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2211-7539 |
| DOI: |
10.1016/j.mmcr.2018.10.005 |
| Popis: |
We report on an elderly male patient with headache and right-side weakness. Imaging studies revealed multiple space-occupying lesions in the parietal and occipital cerebral regions. Biopsy revealed broad aseptate ribbon-like structures branching at right angles, suggestive of mucormycosis. Improvement was observed after medical therapy with 20 weeks of liposomal amphotericin B (5 mg/kg/day) combined with posaconazole, followed by posaconazole (400 mg twice a day) alone for 1 month. The patient recovered without neurological deficits; however, multidrug-resistant bacteraemia and hospital-acquired pneumonia occurred, resulting in death.Nevertheless, our report shows that this lethal fungal infection can sometimes show favourable progress with drug therapy alone. Keywords: Cerebral mucormycosis, Liposomal amphotericin B, Posaconazole, Fungal infection, Antifungal therapy |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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