Assessment of lung hyperinflation in occupational chronic obstructive pulmonary disease: a multicentric cross-sectional study

Autor: Olivier Le Rouzic, Pascal Andujar, Sébastien Hulo, Virginie de Broucker, Pierre-Marie Wardyn, Nadège Lepage, Jean-Louis Edmé
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Druh dokumentu: article
ISSN: 2052-4439
DOI: 10.1136/bmjresp-2023-001846
Popis: Material and methods An overall ‘whole working life’ cumulative exposure index was calculated for occupational patients with COPD. Spirometry indices and lung volumes were measured according to the 2005 American Thoracic Society/European Respiratory Society guidelines.Results After adjustment for age, sex, height, body mass index, smoking and coexposure, the analysis for each occupational hazard showed a higher risk for hyperinflation and FEV1 decline or progression of COPD or GOLD stage for patients with COPD exposed to non-metallic inorganic dusts.Conclusion Occupational exposures should be more investigated in clinical practice and studies as they contribute to the COPD heterogeneity and are associated for some with the development of a static hyperinflation; a condition that is known to have a negative impact on quality of life and survival.
Databáze: Directory of Open Access Journals