HIV Reservoir Decay and CD4 Recovery Associated With High CD8 Counts in Immune Restored Patients on Long-Term ART

Autor:	Lu-Xue Zhang, Yan-Mei Jiao, Chao Zhang, Jin-Wen Song, Xing Fan, Ruo-Nan Xu, Hui-Huang Huang, Ji-Yuan Zhang, Li-Feng Wang, Chun-Bao Zhou, Lei Jin, Ming Shi, Fu-Sheng Wang
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	HIV CD8 counts reservoir decay CD4 recovery long-term antiretroviral therapy Immunologic diseases. Allergy RC581-607
Zdroj:	Frontiers in Immunology, Vol 11 (2020)
Druh dokumentu:	article
ISSN:	1664-3224 46645888
DOI:	10.3389/fimmu.2020.01541
Popis:	Background: Whether varying CD8 counts influence the human immunodeficiency virus (HIV) reservoir and CD4 restoration in patients with CD4 counts ≥ 500 cells/μL after long-term antiretroviral therapy (ART) remains unknown. In this study, we analyzed relationships between CD8 levels and viral reservoir decay or CD4 recovery in immune restored patients on long-term ART.Methods: Chronic HIV-infected patients who received 5 years of ART with CD4 counts ≥ 500 cells/μL were grouped according to CD8 counts: CD8
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6c011ed9a4664588826d00ccc5ec64e8 Zobrazit plný text záznamu View record in DOAJ