Patients with Spondylodiscitis following Chemoradiotherapy for Head and Neck Cancer in a Portuguese Cancer Hospital: A Case Report

Autor: Diana Pessoa, Inês Vicente, Carolina Pereira, Ana Pina, Pedro Freitas, Alexandra Borges, Isabel Sargento
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Case Reports in Oncology, Vol 17, Iss 1, Pp 556-563 (2024)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000535712
Popis: Introduction: Head and neck cancer is an umbrella term for tumor manifestations across the head and neck regions, including the oral cavity, pharynx (including the naso, oro, and hypopharynx), larynx, and sinuses. Treatment options for head and neck cancer include surgery, radiation therapy, chemotherapy, and immunotherapy, with specific treatment plans depending upon individual tumor location and staging, together with overall patient health status. Furthermore, definitive chemoradiotherapy (CRT) has emerged as a highly effective therapeutic option for locoregional advanced head and neck squamous cell cancer. However, such therapy has also been linked to the development of spondylodiscitis. Spondylodiscitis consists of an infection starting at the vertebral endplates and spreading into the intervertebral discs, typically manifesting in adults. Case Presentation and Conclusion: This case report describes our clinical team’s experience in managing three separate cases of spondylodiscitis following CRT for head and neck tumors that presented at our clinic for diagnosis and treatment in order to identify predisposing factors that underlie the link between CRT and spondylodiscitis.
Databáze: Directory of Open Access Journals
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