Efficacy and Safety of Oral Administration of a Mixture of Probiotic Strains in Patients with Psoriasis: A Randomized Controlled Clinical Trial

Autor: Vicente Navarro-López, Asunción Martínez-Andrés, Ana Ramírez-Boscá, Beatriz Ruzafa-Costas, Eva Núñez-Delegido, Miguel A. Carrión-Gutiérrez, David Prieto-Merino, Francisco Codoñer-Cortés, Daniel Ramón-Vidal, Salvador Genovés-Martínez, Empar Chenoll-Cuadros, José M. Pérez-Orquín, José A. Picó-Monllor, Sara Chumillas-Lidón
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Acta Dermato-Venereologica, Vol 99, Iss 12, Pp 1078-1084 (2019)
Druh dokumentu: article
ISSN: 0001-5555
1651-2057
00015555
DOI: 10.2340/00015555-3305
Popis: The aim of this 12-week randomized, double-blind, placebo-controlled trial was to determine the efficacy and safety of a probiotic mixture in the reduction of psoriasis severity. Ninety 18–70-year-old adults with plaque psoriasis were randomized into probiotic and placebo groups. At 12-week follow-up, 66.7% of patients in the probiotic group and 41.9% in the placebo group showed a reduction in Psoriasis Area and Severity Index of up to 75% (p
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