| Autor: |
Celeste A. Roney, Veera Arora, Padmakar V. Kulkarni, Peter P. Antich, Frederick J. Bonte |
| Jazyk: |
angličtina |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
International Journal of Alzheimer's Disease, Vol 2009 (2009) |
| Druh dokumentu: |
article |
| ISSN: |
2090-0252 |
| DOI: |
10.4061/2009/481031 |
| Popis: |
Detecting aggregated amyloid peptides (Aβ plaques) presents targets for developing biomarkers of Alzheimer's disease (AD). Polymeric n-butyl-2-cyanoacrylate (PBCA) nanoparticles (NPs) were encapsulated with radiolabelled amyloid affinity I125-clioquinol (CQ, 5-chloro-7-iodo-8-hydroxyquinoline) as in vivo probes. I125-CQ-PBCA NPs crossed the BBB (2.3±0.9 ID/g) (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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