Association between 24-hour diastolic blood pressure and renal function in patients receiving treatment for essential hypertension
| Autor: | J Sveceny, J Charvat, K Hrach, M Horackova, O Schück |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Journal of International Medical Research, Vol 47 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0300-0605 1473-2300 03000605 |
| DOI: | 10.1177/0300060519867805 |
| Popis: | Objectives To evaluate the association between diastolic blood pressure (BP), measured by 24-hour ambulatory blood pressure monitoring (ABPM) and renal function in patients receiving treatment for essential hypertension. Methods In this cross-sectional study, ABPM, transthoracic echocardiography, estimated glomerular filtration rate (eGFR) on the basis of serum cystatin C (eGFRcyst) and the renal resistive index (RRI) were measured in patients with essential hypertension. Results The cohort consisted of 105 patients (39 men, 66 women), with a mean ± SD age of 58 ± 12 years who had been receiving treatment for 11 ± 8 years. 24-hour diastolic BP significantly positively correlated with eGFRcyst and negatively correlated with RRI. No correlation was observed with 24-hour systolic BP values. 24-hour diastolic BP values ≤70 mmHg were associated with eGFRcyst ≤60 ml/min/1.73 m 2 (i.e., decreased GFR). Conclusion 24-hour diastolic BP values were significantly associated with markers of kidney function in patients receiving treatment for essential hypertension and values ≤70 mmHg may be associated with subnormal eGFRcyst. |
| Databáze: | Directory of Open Access Journals |
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