Antiretroviral therapy reduces HIV transmission in discordant couples in rural Yunnan, China.

Autor: Na He, Song Duan, Yingying Ding, Keming Rou, Jennifer M McGoogan, Manhong Jia, Yuecheng Yang, Jibao Wang, Julio S G Montaner, Zunyou Wu, China National HIV Prevention Study Group
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: PLoS ONE, Vol 8, Iss 11, p e77981 (2013)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0077981
Popis: BACKGROUND: Although HIV treatment as prevention (TasP) via early antiretroviral therapy (ART) has proven to reduce transmissions among HIV-serodiscordant couples, its full implementation in developing countries remains a challenge. In this study, we determine whether China's current HIV treatment program prevents new HIV infections among discordant couples in rural China. METHODS: A prospective, longitudinal cohort study was conducted from June 2009 to March 2011, in rural Yunnan. A total of 1,618 HIV-discordant couples were eligible, 1,101 were enrolled, and 813 were followed for an average of 1.4 person-years (PY). Routine ART was prescribed to HIV-positive spouses according to eligibility (CD4
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