Evaluation of Tp-e interval and Tp-e/QT ratio in patients with rheumatoid arthritis

Autor: Gurkan Acar, Murat Akkoyun, Alper Buğra Nacar, İmran Dirnak, Gözde Yıldırım Çetin, Makbule Nur Yıldırım, Cemil Zencir, Kayıhan Karaman, Mustafa Çetin, Mehmet Sayarlıoğlu
Jazyk: English<br />Turkish
Rok vydání: 2014
Předmět:
Zdroj: Türk Kardiyoloji Derneği Arşivi, Vol 42, Iss 1, Pp 29-34 (2014)
Druh dokumentu: article
ISSN: 1016-5169
DOI: 10.5543/tkda.2014/52959
Popis: Objective: Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and that inreased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. The aim of this study was to evaluate ventricular repolarization by using Tp-e interval and Tp-e/QT ratio in patients with rheumatoid arthritis (RA), and to assess the relation with inflammation. Study design: Ninety-six patients with RA and and 50 controls were included. From the 12-lead electrocardiogram Tp-e interval and Tp-e/QT ratio were measured. Blood samples were taken for erythrocyte sedimentation rate (ESR) and plasma levels of C-reactive protein (CRP). These parameters were compared between groups. The relationship between ventricular repolarization and inflammation was assessed by Pearson correlation coefficients. Results: Tp-e interval and Tp-e/QT ratio were increased in RA patients compared to the controls (72.6+-8.2 vs 66.4+-8.5 milliseconds, 0.20 +- 0.02 vs 0.18 +- 0.02; P
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