Spectacular skin nodules: Cutaneous necrobiotic xanthogranuloma without paraproteinemia

Autor: Shimoni Kadakia, Nitin Nadkarni, Sham Sonavane, Sunil Ghate
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Indian Journal of Dermatology, Vol 57, Iss 5, Pp 396-398 (2012)
Druh dokumentu: article
ISSN: 0019-5154
1998-3611
DOI: 10.4103/0019-5154.100499
Popis: Necrobiotic xanthogranuloma (NXG) is a very rare, progressive variant of non-Langerhans cell histiocytosis. It is known to be associated with multisystem involvement and paraproteinemias. A 65-year-old female presented with chronic, slowly growing, asymptomatic periorbital nodules. The lesions had recurred after local excision elsewhere. No systemic involvement or paraproteinemias were detected. A provisional diagnosis of isolated cutaneous NXG was made which was confirmed by histopathology and immunohistochemistry staining. The lesions were surgically excised with excellent cosmetic and functional results. There was no recurrence over a period of 9 months. To our knowledge, this is the second case of NXG reported from India and the first without any systemic manifestations.
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