| Autor: |
Zhuang Han, Yong-Xin Li, Ling-Li Liu, Liang Lu, Xian-Rong Guo, Xi-Xiang Zhang, Xiao-Yong Zhang, Shu-Hua Qi, Ying Xu, Pei-Yuan Qian |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Marine Drugs, Vol 15, Iss 5, p 128 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1660-3397 |
| DOI: |
10.3390/md15050128 |
| Popis: |
Eleven new depsides—thielavins W–Z (1–4) and thielavins Z1–Z7 (5–11)—and also four known thielavins—A, H, J, and K (12–15)—were isolated from the ethyl acetate extract of a marine-derived fungal strain Thielavia sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle Balanus (=Amphibalanus) amphitrite. The results showed that compounds 1–3 and 6–13 were active, with EC50 values ranging from 2.95 ± 0.59 to 69.19 ± 9.51 μM, respectively. The inhibitive effect of compounds 1–3 and 7 was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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