The hierarchical assembly of septins revealed by high-speed AFM

Autor: Fang Jiao, Kevin S. Cannon, Yi-Chih Lin, Amy S. Gladfelter, Simon Scheuring
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18778-x
Popis: Septins are GTP-binding proteins involved in diverse cellular processes including division, polarity maintenance and membrane remodeling. Here authors use high-speed atomic force microscopy to show that assembly of septin filaments is a diffusion-driven process, while septin assembly into higher-order involves septin self-templating
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