Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse)

Autor: Marine Isakadze, Benjamin Zwain, Alan J. Velander, Jesus Lovera
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: eNeurologicalSci, Vol 34, Iss , Pp 100488- (2024)
Druh dokumentu: article
ISSN: 2405-6502
DOI: 10.1016/j.ensci.2023.100488
Popis: Central hypoventilation syndrome (CHS) is a rare condition resulting from damage to the respiratory centers in the central nervous system (CNS). It can be congenital or acquired and can cause hypoventilation, inadequate gas exchange, and respiratory failure, often during sleep but sometimes even while awake. CHS can lead to respiratory failure and life-threatening complications if not identified promptly. In this report, we present a rare case of a patient with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), who developed CHS likely due to an opportunistic infection by cytomegalovirus (CMV) and varicella zoster virus (VZV), manifesting as a lesion in the medullary respiratory nuclei. After treatment with ganciclovir, the patient showed clinical improvement, and his medullary lesion resolved.
Databáze: Directory of Open Access Journals