Value of myocardial deformation parameters for detecting significant coronary artery disease
| Autor: | Egle Rumbinaite, Arnas Karuzas, Dovydas Verikas, Ieva Jonauskiene, Olivija Gustiene, Arslan Mamedov, Loreta Jankauskiene, Rimantas Benetis, Remigijus Zaliunas, Jolanta Justina Vaskelyte |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Cardiovascular and Thoracic Research, Vol 14, Iss 3, Pp 180-190 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2008-5117 2008-6830 |
| DOI: | 10.34172/jcvtr.2022.30 |
| Popis: | Introduction: The study aimed to evaluate the diagnostic value of global and regional myocardial deformation parameters derived from two-dimensional speckle-tracking echocardiography to detect functionally significant coronary artery stenosis. Methods: Dobutamine stress echocardiography and cardiac magnetic resonance myocardial perfusion imaging (CMR-MPI) were performed on 145 patients with a moderate and high probability of coronary artery disease (CAD) and LVEF≥55%. Significant CAD was defined as>50% stenosis of the left main stem,>70% stenosis in a major coronary vessel, or in the presence of intermediate stenosis (50-69%) validated as hemodynamically significant by CMRMPI. Patients were divided in two groups: non-pathological (48.3%) vs pathological (51.7%), according to CAG and CMR-MPI results. Afterwards, off-line speckle-tracking analysis was performed to analyse myocardial deformation parameters. Results: There were no differences in myocardial deformation parameters at rest between groups, except global longitudinal strain (GLS) and global radial strain (GRS) were significantly lower in the CAD (+) group: -21.3±2.2 vs.-16.3±2.3 (P |
| Databáze: | Directory of Open Access Journals |
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