| Autor: |
Bahram Eshraghi, Behzad Khademi, Majid Mirmohammadkhani, Gholamreza Khataminia, Hossein Ghahvehchian, Mohammad Yaser Kiarudi, Reza Nabie, Mohammadmehdi Parandin, Paria Ghasemi Boroumand, Rasoul Mohammadi, Zahra Zia, Soroush Karamirad, Soheyla Jafarpour, Mostafa Fakoor, Mojtaba Varshochi, Kourosh Shahraki, Mohammad Memarzadeh, Masoud Janipour, Atefe Mahdian Rad, Mohsen B Kashkouli, Farid Shekarchian, Vahideh Manouchehri, Abbas Khosravi, Mahdi Abounoori, Abazar Shahir, S. Mohammad Javad Sajjadi, Mohammad Etezad Razavi, Nastaran-Sadat Hosseini, Fatemeh Ebrahimi, Pegah Noorshargh, Ali Forouhari, Mohsen Pourazizi |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-14 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2334 |
| DOI: |
10.1186/s12879-024-09755-6 |
| Popis: |
Abstract Background To evaluate the demographic, clinical, and prognostic characteristics of patients diagnosed with COVID-19-associated mucormycosis (CAM) in Iranian patients. Methods This prospective observational study was conducted in 8 tertiary referral ophthalmology centers in different provinces of Iran during the fifth wave of the COVID-19 pandemic. All patients were subjected to complete history taking and comprehensive ophthalmological examination and underwent standard accepted treatment strategy based on the disease stage. Results Two hundred seventy-four CAM patients (most were males (150, 54.7%)) with a mean age of 56.8 ± 12.44 years were enrolled. Patients with a history of cigarette smoking (Adjusted Odds Ratio (AOR) = 4.36), Intensive Care Unit admission (ICU) (AOR = 16.26), higher stage of CAM (AOR = 2.72), and receiving endoscopic debridement and transcutaneous retrobulbar amphotericin B (AOR = 3.30) had higher odds of mortality. History of taking systemic corticosteroids during COVID-19 was significantly associated with reduced odds of mortality (AOR = 0.16). Generalized Estimating Equations analysis showed that the visual acuity of deceased patients (LogMAR: 3.71, 95% CI: 3.04–4.38) was worse than that of patients who were discharged from the hospital (LogMAR: 2.42, 95% CI: 2.16–2.68) (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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