Shunt-Dependent Post-Traumatic Hydrocephalus: Predictors and Long-Term Functional Outcomes

Autor: Hao Xu, Yongfei Dong, Dejun Bao, Xiangpin Wei, Chaoshi Niu, Xinfeng Liu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Neurology and Therapy, Vol 12, Iss 5, Pp 1607-1622 (2023)
Druh dokumentu: article
ISSN: 2193-8253
2193-6536
DOI: 10.1007/s40120-023-00511-7
Popis: Abstract Introduction As a disorder of the brain in adults and children, traumatic brain injury (TBI) is considered the major cause of mortality and morbidity. As a serious complication of TBI, post-traumatic hydrocephalus (PTH) is commonly identified and significantly associated with neurocognitive impairment, motor dysfunction, and growth impairment. The long-term functional outcomes after shunt dependence are totally not clear. Methods This study included 6279 patients between 2012 and 2022. To identify the unfavorable functional outcomes and the PTH-related factors, we carried out univariable logistic regression analyses. To identify the occurrence time of PTH, we conducted the log-rank test and Kaplan–Meier analysis. Results Mean patient age was 51.03 ± 22.09 years. Of the 6279 patients with TBI, 327 developed PTH (5.2%). Several PTH development-associated factors, such as intracerebral hematoma, diabetes, longer initial hospital stay, craniotomy, low GCS (Glasgow Coma Scale), EVD (external ventricular drain), and DC (decompressive craniectomy) (p 80 years, repeated operations, hypertension, EVD, tracheotomy, and epilepsy (p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje