Síntese e caracterização de beads acrílicos preparados por polimerização em suspensão visando aplicação como excipiente farmacêutico para compressão direta
| Autor: | Janaina Cecília Oliveira Villanova, Tadeu Henrique Lima, Patrícia Santiago Patrício, Fabiano Vargas Pereira, Eliane Ayres |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Química Nova, Vol 35, Iss 1, Pp 124-131 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1678-7064 0100-4042 |
| DOI: | 10.1590/S0100-40422012000100023 |
| Popis: | One of the difficulties reported for the suspension polymerization is control the size and granulometry of beads. The purpose of this work was to evaluate the use of cellulose nanowhiskers and mesoporous silica as stabilizers to reduce the size and the particle distribution. To monitor polymerization process was used FTIR-ATR spectroscopy. The morphology was analyzed by scanning electron microscopy. The particle size distribution was characterised using a CILAS granulometer. Thermal stability was studied by thermogravimetric analysis. The results indicated that cellulose nanowhiskers may provide stabilization and increase the thermal stability of the beads in contrast to mesoporous silica. |
| Databáze: | Directory of Open Access Journals |
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