Corneal endothelial changes in patients with chronic kidney disease

Autor: Shahira Mahmoud, Yasmine S Naga, Mohab El Khabiry, Mahmoud Hassan Morsy
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Delta Journal of Ophthalmology, Vol 22, Iss 4, Pp 265-269 (2021)
Druh dokumentu: article
ISSN: 1110-9173
2090-4835
DOI: 10.4103/djo.djo_30_21
Popis: Purpose The aim of this study was to assess the effect of chronic kidney disease and duration of hemodialysis on the corneal endothelium. Patients and methods This case–control study included 78 participants who were divided into three groups: group I: the dialyzed group, group II: the nondialyzed group, and group III: age-matched control group. The endothelial cell density (ECD), average area of endothelial cells, SD, coefficient of variation, percentage of hexagonal cells, and central corneal thickness (CCT) were compared between the three groups. The effect of blood urea, serum creatinine, and duration of dialysis on corneal endothelium was studied in the dialyzed group. Results The ECD was statistically significantly less in the dialyzed group compared with the nondialyzed and control groups (2345.19±307.34, 2428.46±349.38, and 2481.23±286.16 cells/mm2, respectively, P
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