Too old for healthy aging? Exploring age limits of longevity treatments

Autor: Prerana Shrikant Chaudhari, Maria A. Ermolaeva
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-9 (2024)
Druh dokumentu: article
ISSN: 2948-2828
47209127
DOI: 10.1038/s44324-024-00040-3
Popis: Abstract It is well documented that aging elicits metabolic failures, while poor metabolism contributes to accelerated aging. Metabolism in general, and energy metabolism in particular are also effective entry points for interventions that extend lifespan and improve organ function during aging. In this review, we discuss common metabolic remedies for healthy aging from the angle of their potential age-specificity. We demonstrate that some well-known metabolic treatments are mostly effective in young and middle-aged organisms, while others maintain high efficacy independently of age. The mechanistic basis of presence or lack of the age limitations is laid out and discussed.
Databáze: Directory of Open Access Journals
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