| Autor: |
Luca Castagna, Stefania Tringali, Giuseppe Sapienza, Roberto Bono, Rosario Di Maggio, Aurelio Maggio |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Thalassemia Reports, Vol 13, Iss 2, Pp 122-130 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2039-4365 |
| DOI: |
10.3390/thalassrep13020011 |
| Popis: |
Allogeneic stem cell transplantation remains the only therapy for congenital, severe haemoglobinopathies that is able to reverse the pathological phenotype. In the severe form of thalassemia, regular transfusions are needed early in life. This population of patients could benefit from allo-SCT. However, the great efficacy of transplantation must be counterbalanced by the mortality and morbidity related to the procedure. In this short review, we reviewed the most recent data in the field of transplantation in transfusion-dependent thalassemia (TDT), highlighting the factors that have a major impact on outcomes. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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