Genome Destabilization Upon Exposure to Ionizing Radiation and During Acute Blood Loss

Autor:	V. L. Kozhura, N. V. Kondakova, S. I. Zaichkina, O. M. Rozanova
Jazyk:	English<br />Russian
Rok vydání:	2007
Předmět:	acute blood loss ionizing radiation genome destabilization bone marrow micronuclear test Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Zdroj:	Общая реаниматология, Vol 3, Iss 1, Pp 5-11 (2007)
Druh dokumentu:	article
ISSN:	1813-9779 2411-7110
DOI:	10.15360/1813-9779-2007-1-5-11
Popis:	The paper compares the currently available cytogenetic methods (chromosomal aberration test and micronuclear (MN) test) for the evaluation of the impact of stressors, by using ionizing radiation as an example. The experimental findings have led to the conclusion that the MN test shows the status of genome and reveals lesions upon very weak exposures. The MN test has demonstrated that hemic hypoxia and reinfusion, as other stressors, cause genetic material destabiliza-tion.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6b7486a537da41f3ac76dfcf2086f40d Zobrazit plný text záznamu View record in DOAJ