Late-onset bleb-associated endophthalmitis and continuous positive airway pressure

Autor: Erich J. Berg, John B. Davies, Mark R. Buboltz, Thomas W. Samuelson
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: American Journal of Ophthalmology Case Reports, Vol 10, Iss , Pp 87-90 (2018)
Druh dokumentu: article
ISSN: 2451-9936
DOI: 10.1016/j.ajoc.2018.02.007
Popis: Purpose: To raise awareness of a possible association between continuous positive airway pressure (CPAP) devices and postoperative bleb-related infection. Observations: A 57-year old patient on CPAP presented with unilateral bleb-associated endophthalmitis 32 months after routine ExPress Trabeculectomy with mitomycin C. The offending organism, Streptococcus mitis, is a nonmotile and generally non-virulent pathogen which predominates in the normal human respiratory flora. Conclusions and importance: This conceptual report underscores a potential relationship between CPAP use and bleb-associated endophthalmitis. Streptococcal species are the most commonly reported causative organisms in bleb-associated endophthalmitis, and S. mitis is of particular concern as the most abundant microbe among all human oral flora. A logical risk factor for infection, the CPAP device may inadvertently deliver such organisms to the vulnerable conjunctival filtering bleb. Keywords: Endophthalmitis, Bleb, Mitomycin C, Express trabeculectomy, Continuous positive airway pressure, Streptococcus mitis
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