Identification and resolution of drug-related problems among neonates in neonatal intensive care unit (NICU): A prospective longitudinal observational study

Autor: Pooja Dwivedi, Sujit Kumar Sah, Srinivasa Murthy, Madhan Ramesh
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical Epidemiology and Global Health, Vol 29, Iss , Pp 101728- (2024)
Druh dokumentu: article
ISSN: 2213-3984
DOI: 10.1016/j.cegh.2024.101728
Popis: Background: Drug related problems (DRPs) can interfere with the desired therapeutic outcomes. Neonates are susceptible for DRP occurrence due to clinical heterogeneity, inappropriate formulations, complexity of drug regimens and polypharmacy. Thus, the objective of this study was to characterize the DRP, their resolutions and associated risk factors among neonates in the Neonatal Intensive Care Unit (NICU). Methods: A cross-sectional study was carried out in NICU ward at tertiary care teaching hospital for 18 months. Clinical pharmacists participated on daily basis to collect patient information and assess their medication therapy for DRPs. DRPs were classified into problems and their causes according to Pharmaceutical Care Network Europe (PCNE) Version 9.1. Clinical pharmacist implicated evidence-based interventions to resolve DRPs. SPSS V.25 was used for the statistical analysis. Univariate logistic regression analysis was used for the determination of risk factors for DRPs, with a p-value
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