Molecular Cloning of Monkey Histamine H4 Receptor

Autor: Tamaki Oda, Shun-ichiro Matsumoto, Mitsuyuki Matsumoto, Jun Takasaki, Masazumi Kamohara, Takatoshi Soga, Hideki Hiyama, Masato Kobori, Masao Katoh
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Zdroj: Journal of Pharmacological Sciences, Vol 98, Iss 3, Pp 319-322 (2005)
Druh dokumentu: article
ISSN: 1347-8613
DOI: 10.1254/jphs.sc0050033
Popis: Histamine H4 receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H4 receptor was identified. Monkey H4 receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H4 receptor will contribute to a better interpretation of effective drug discovery. Keywords:: histamine, H4 receptor, G-protein coupled receptor
Databáze: Directory of Open Access Journals