| Autor: |
Carlota Dobaño, Hèctor Sanz, Hermann Sorgho, David Dosoo, Maximilian Mpina, Itziar Ubillos, Ruth Aguilar, Tom Ford, Núria Díez-Padrisa, Nana Aba Williams, Aintzane Ayestaran, Ousmane Traore, Augusto J. Nhabomba, Chenjerai Jairoce, John Waitumbi, Selidji Todagbe Agnandji, Simon Kariuki, Salim Abdulla, John J. Aponte, Benjamin Mordmüller, Kwaku Poku Asante, Seth Owusu-Agyei, Halidou Tinto, Joseph J. Campo, Gemma Moncunill, Ben Gyan, Clarissa Valim, Claudia Daubenberger |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-10195-z |
| Popis: |
RTS,S/AS01E has been tested in a phase 3 malaria vaccine trial and has shown partial efficacy in children and infants. Here, the authors analyze IgG concentration and avidity to CSP in ~1000 participants and show that IgG avidity to the C-terminus of CSP is significantly associated with vaccine-mediated protection. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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