| Autor: |
Carlos Eduardo David de Almeida, Lidia Raquel de Carvalho, Carla Vasconcelos Caspar Andrade, Paulo do Nascimento Jr, Guilherme Antonio Moreira de Barros, Norma Sueli Pinheiro Modolo |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Brazilian Journal of Anesthesiology, Vol 71, Iss 5, Pp 482-488 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
0104-0014 |
| DOI: |
10.1016/j.bjane.2021.07.023 |
| Popis: |
Background and aims: Rocuronium may provide excellent onset time, but high doses are required for effective action. Several strategies have managed to shorten rocuronium onset time, including the use of Magnesium Sulphate (MgSO4). Methods: One hundred and eighty patients were randomized into six groups according to rocuronium dose received (0.3, 0.6 or 1.2 mg.kg-1) and the administration of saline or MgSO4 (60 mg.kg-1). Correlations between tissue perfusion and rocuronium onset time was determined by variations in perfusion index. Results: Median (quartiles) rocuronium onset times were 85.5 (74.0–92.0); 76.0 (52.0–87.0) and 50.0 (41.0–59.5) seconds for 0.3, 0.6 mg.kg-1 and 1.2 mg.kg-1 doses, respectively. MgSO4 decreased rocuronium onset at doses of 0.3 mg.kg-1 (60.0 [48.0–74.3] seconds) and 0.6 mg.kg-1 (44.0 [39.0–49.0] seconds) but not at 1.2 mg.kg-1 (38.0 [33.5–56.3] seconds) (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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